Statistical issues in clinical trials of inflammatory bowel disease using endoscopy
Event information
Location: Warwick Conference Centre, University of Warwick
Date: 27 April 2015
Working group: Imaging studies
NIHR Statistics Group: Imaging Studies section meeting
Statistical Issues in Clinical Trials of Inflammatory Bowel Disease using Endoscopy
This meeting brought together statisticians, clinicians and other methodologists for discussion of common statistical issues in imaging studies. Challenges were illustrated by examining a clinical example – centralised reading of endoscopy for clinical trials in Inflammatory Bowel Disease – but they are also widely applicable to other imaging modalities.
Statistical issues for discussion in this meeting included:
- Sample size considerations in imaging studies
- Inter-rater agreement and the effect of subjective image assessment
- Reproducibility of endpoint assessment
- Agreement and variability between repeated imaging time-points